The acquisition and use of information are key factors in successful executive performance. Although there are various and different media that executives use to obtain information, in the last decade the academic research has emphasised computer-based systems. Inside this group of systems, we can find the Executive Information Systems (EIS), which are tools that can help executives to obtain relevant information more efficiently. Recently, EIS have been analyzed through the Technology Acceptance Model (TAM) with significant results. A deeper review of these results, the existing literature, as well as our own experience, suggest there are some factors that affect to the use of EIS indirectly or as moderating variables, instead of directly as recent studies suggest. The objective of our research is to propose a framework based on the TAM, which shows the different types of factors that affect to the Perceived Usefulness (PU) and Perceived Ease of Use (PEU) of EIS, as well as how the kind of influence of these factors on PU and PEU.