Elizabeth E UhlenhakeDepartment of Dermatology, Wayne State University School of Medicine, Detroit, MI, USAAbstract: The most compelling reason and primary goal of treating actinic keratoses is to prevent malignant transformation into invasive squamous cell carcinoma, and although there are well established guidelines outlining treatment modalities and regimens for squamous cell carcinoma, the more commonly encountered precancerous actinic lesions have no such standard. Many options are available with variable success and patient compliance rates. Prevention of these lesions is key, with sun protection being a must in treating aging patients with sun damage as it is never too late to begin protecting the skin.Keywords: actinic keratosis, photodynamic therapy, topical chemotherapy, field therapyA Letter to the Editor has been received and published for this article.