Interprofessional education (IPE) is a required component of the nursing curriculum as it can foster students' abilities to become integral members of the health care team. To facilitate this requirement, an IPE experience focusing on cardiovascular pharmacology was created for nurse practitioner and physician assistant students. The authors developed and utilized a problem-based learning activity and two minicase scenarios. The Student Perceptions of Physician-Pharmacist Interprofessional Clinical Education-Revised was administered before and after the activity to assess students' attitudes toward IPE. This article reviews the planning, development, and implementation of this IPE experience and discusses its challenges.