Estrogen-related receptor gamma functions as a tumor suppressor in gastric cancer

Estrogen-related receptor gamma functions as a tumor suppressor in gastric cancer

Kang, Myoung-Hee;Choi, Hyunji;Oshima, Masanobu;Cheong, Jae-Ho;Kim, Seokho;Lee, Jung Hoon;Park, Young Soo;Choi, Hueng-Sik;Kweon, Mi-Na;Pack, Chan-Gi;Lee, Ju-Seog;Mills, Gordon B.;Myung, Seung-Jae;Park, Yun-Yong;
Nature communications 2018 Vol. 9 pp. 1-13
208
kang2018estrogenrelatednature

Abstract

Very little is known regarding the molecular mechanisms involved in gastric cancer development. Here the authors show estrogen-related receptor gamma (ESRRG) is a tumor suppressor in gastric cancer and suggest the mechanism of this tumor suppression function involves the inhibition of Wnt signaling.

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