Nursing education is being challenged to rapidly evolve in order to meet the complex and systemic health care demands facing societies globally. International immersion is one educational strategy promoted to help prepare nursing students to meet these challenges. The Comparative Health Care Immersion Course in South Korea was created to educate entry-level master of science in nursing (MSN) students studying to become Clinical Nurse Leaders (CNL) to meet the complex systems level challenges facing health care organizations in the United States. Teaching adults in a cross-cultural setting required a complex philosophical and andragogical approach weaving together cultural constructivism, cultural attunement, anti-imperialism, critical theory, and experiential learning.