An adiabatic connection (AC) is developed as an electron correlation correction for doubly occupied configuration interaction (DOCI) wave functions. Following the work of Pernal [Phys. Rev. Lett. 120, 013001 (2018)], the working equations of the approach, termed AC-DOCI, are rooted in the extended random phase approximation (ERPA) and require knowledge of only the ground-state two-electron reduced density matrix (2RDM) from the DOCI. As such, the AC is naturally suited to modeling electron correlation in variational 2RDM (v2RDM)-based approximations to the DOCI. The v2RDM-driven AC-DOCI is applied to the dissociation of molecular nitrogen and the double dissociation of water; the approach yields energies that are similar in quality to those from second-order multireference perturbation theory near equilibrium, but the quality of the AC-DOCI energy degrades at stretched geometries. The exact adiabatic connection path suggests the assumption that the one-electron reduced-density matrix is constant along the AC path is invalid at stretched geometries, but this deficiency alone cannot explain the observed behavior. Rather, it appears that the ERPA's single-particle-transition ansatz cannot, in general, provide good approximations to the 2RDM along the AC path. The AC-DOCI is also applied to a set of 45 reaction energies; for these systems, the approach has an average accuracy that is comparable to that of single-reference second-order many-body perturbation theory.