The realization of optical interconnects between multimode (MM) optical fibers and waveguides based on a self-writing process in photopolymer media represents an efficient approach for fast and easy-to-implement connection of light-guiding elements. When light propagates through photopolymer media, it modulates the material properties of the media and confines the spreading of the light beam to create a waveguide along the beam propagation direction. This self-writing process can be realized with a single photopolymer medium and is also suited to connect optical fibers or waveguides with active elements such as light sources and detectors. Numerical simulations of the underlying light-induced polymerization process is carried out by using a diffusion based material model which takes account both monomer diffusion and its conversion to polymer chains in regions exposed to light fields. In this work experimental results obtained from a one-polymer approach are validated with theoretical predictions from the diffusion model. The study involved the demonstration of temporal dynamics and transmittance from self-written waveguide (SWW) couplers during the self-writing process. The measured attenuation coefficient from experiment α = (8.43 ± 0.3) × 10 dB/µm showed good agreement with the theoretically predicted attenuation coefficient α = 7.93 × 10 dB/µm, thus demonstrating a successful application of the diffusion model to epoxy based acrylate SWWs. For comparison, attenuation measurements between optical fibers with SWWs as interconnects and one without SWW, i.e. with an air gap in between, were performed. The obtained results reveal that the theoretical approach correctly describes the waveguide formation process so that in the next step the studies can be extended towards including further relevant parameters such as temperature.