Quality of life in adolescence period determines individual's future. The effect of maternal employment on children's quality of life is important and undeniable issue. This study aimed to investigate and compare the quality of life among children of employed and housewife women. In this study, the participants included selected school children's employed and housewife mothers. The tools for data collection consisted of a questionnaire which was distributed among 671 middle-high school and high school students (304 have employed mothers and 367 have housewives mothers. In this study, the level of significance was considered. Results showed that the life quality of children of employed mothers and housewife mothers in the two groups is statistically significant. Quality of life in employed mothers in the mental, physical, social relations, emotional, religious, achieve life goals, leisure time and economic dimension were higher than housewife mothers but there was not any significant different among employed mothers' children and housewife mothers' children in dimensions of relationships with parents. Girls' quality of Life was more than boys, in the teacher mothers was higher than other occupations and in the exceptional talents school was more than other schools. This study found that maternal employment has effect on children's quality of life, so employed mothers' children have high quality of life.