The intervertebral disc (IVD) is essential for the mobility and stability of the spine. During flexion-distraction injuries, which are frequent at the cervical spine level, the IVD is often disrupted. Finite element studies have been done to investigate injury mechanisms and patterns at the cervical spine. However, they rarely include IVD failure model. The aim of this paper was to implement and compare two types of IVD failure models and their impact on hyperflexion and hyperflexion-compression injuries simulations. The failure models were tested on a detailed C4-C5 finite elements model. The first failure model consisted in a maximal strain model applied to the elements of the annulus and nucleus. The second failure model consisted in the implementation of a rupture plane in the middle of the IVD with a tied interface created between the two sections. This interface is defined by threshold stress values of detachment in traction and shearing. The two failure models were tested in flexion only and in flexion-compression. The model without inclusion of an IVD failure model was also tested. Loads at failure and injury patterns were reported. Both failure models produce failure loads that were consistent with experimental data. Injury patterns observed were in agreement with experimental and numerical studies. However, in flexion-compression, the rupture plane model simulation reached important energy error due to high deformations in the IVD elements. Also, without inclusion of an IVD failure model, energy error forced the end of the simulation in flexion-compression. Therefore, inclusion of IVD failure model is important since it leads to realistic results, but the maximal strain failure model is recommended.