The current empirical study explores the linkage between carbon dioxide (CO) emissions, average temperature, cultivated area, consumption of fertilizer, and rice production in Pakistan. For this research, the annual time series data from 1968 to 2014 were used to enhance the validity of the empirical outcomes. The cointegration analysis with the auto-regressive distributed lag (ARDL) bounds testing approach is applied to explore the effects of climate change on rice production. Additionally, the estimated long-run outcomes are verified by employing fully modified ordinary least squared (FMOLS) and canonical cointegrating regression (CCR) approaches. The empirical outcomes revealed that the selected important study variables are cointegrated demonstrating the existence of long-run linkages among them. The main fruitful outcomes of this study are that rice production in Pakistan is positively affected by the carbon dioxide (CO) emissions in both long-run and short-run.