Identifying Cancer Targets Based on Machine Learning Methods via Chou's 5-steps Rule and General Pseudo Components.

Identifying Cancer Targets Based on Machine Learning Methods via Chou's 5-steps Rule and General Pseudo Components.

Liang, Ruirui;Xie, Jiayang;Zhang, Chi;Zhang, Mengying;Huang, Hai;Huo, Haizhong;Cao, Xin;Niu, Bing;
Current topics in medicinal chemistry 2019 Vol. 19 pp. 2301-2317
308
liang2019identifyingcurrent

Abstract

In recent years, the successful implementation of human genome project has made people realize that genetic, environmental and lifestyle factors should be combined together to study cancer due to the complexity and various forms of the disease. The increasing availability and growth rate of 'big data' derived from various omics, opens a new window for study and therapy of cancer. In this paper, we will introduce the application of machine learning methods in handling cancer big data including the use of artificial neural networks, support vector machines, ensemble learning and naïve Bayes classifiers.

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