Acute Myeloid Leukemia with Concomitant BCR-ABL and NPM1 Mutations
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Acute Myeloid Leukemia with Concomitant BCR-ABL and NPM1 Mutations

Mariotti, Benedetta;Meconi, Federico;Palmieri, Raffaele;De Bellis, Eleonora;Lavorgna, Serena;Ottone, Tiziana;Martini, Vincenza;Lo-Coco, Francesco;Cicconi, Laura;Mariotti, Benedetta;Meconi, Federico;Palmieri, Raffaele;De Bellis, Eleonora;Lavorgna, Serena;Ottone, Tiziana;Martini, Vincenza;Lo-Coco, Francesco;Cicconi, Laura;
case reports in hematology 2019 Vol. 2019
352
benedetta2019acutecase

Abstract

We present a case report of a patient with acute myeloid leukemia (AML) characterized by the simultaneous presence of nucleophosmin 1 (NPM1) mutation and the breakpoint cluster region-Abelson (BCR-ABL) fusion oncogene. Our findings emphasize the importance of routinely including BCR-ABL in the diagnostic workup of AML in order to offer to the patients the most appropriate risk category and treatment options.

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DOI:
10.1155/2019/6707506
URL:
https://www.hindawi.com/journals/crihem/2019/67075...

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ID: 7959
Ref Key: benedetta2019acutecase
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