Cycloartane triterpenoids from Pseudolarix amabilis and their antiviral activity.
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Cycloartane triterpenoids from Pseudolarix amabilis and their antiviral activity.

Zhao, Xiao-Tong;Yu, Mei-Hua;Su, Shi-Yun;Shi, Xun-Long;Lei, Chun;Hou, Ai-Jun;
Phytochemistry 2020 Vol. 171 pp. 112229
274
zhao2020cycloartanephytochemistry

Abstract

Seven undescribed cycloartane triterpenoids, pseudolarnoids A-G, together with ten known ones, were isolated from the seeds of Pseudolarix amabilis (J. Nelson) Rehder. Their structures were elucidated on the basis of spectroscopic analysis, X-ray crystallography, and ECD data. Pseudolarnoids A-C are cycloartane triterpenoids with a unique 16S, 23R-spirolactone moiety. Pseudolarnoids F, G, and pseudolarolide C demonstrated potent antiviral effects on HSV-1 in vitro.

Keywords

antiviral activity cycloartane triterpenoids pinaceae pseudolarix amabilis (j. nelson) rehder pseudolarnoids a−g

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DOI:
S0031-9422(19)30933-1

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