New thermosets from a triglycidyl eugenol derivative (3EPOEU) as a renewable epoxy monomer were obtained by an epoxy-amine curing process. A commercially-available Jeffamine and isophorone diamine, both obtained from renewable resources, were used as crosslinking agents, and the materials obtained were compared with those obtained from a standard diglycidylether of bisphenol A (DGEBA). The evolution of the curing process was studied by differential scanning calorimetry and the materials obtained were characterized by means of calorimetry, thermogravimetry, thermodynamomechanical analysis, stress-strain tests and microindentation. 3EPOEU formulations were slightly less reactive, and the thermosets obtained showed higher s than those prepared from DGEBA, since they had higher crosslinking density than formulations with DGEBA because of the more compact structure and higher functionality of the eugenol derivative. 3EPOEU thermosets showed good thermal stability and mechanical properties. The results obtained in this study allow us to conclude that the triglycidyl derivative of eugenol, 3EPOEU, is a safe and environmentally friendly alternative to DGEBA.