Mucilage powder from litsea glutinosa leaves stimulates the growth of cultured human hair follicles
Sitthithaworn, W.
songklanakarin journal of science and technology2018Vol. 40pp. 1076-1080
246
sitthithaworn2018mucilagesongklanakarin
Abstract
The cleaning property of mucilage from the leaves of Litsea glutinosa (Lour.) C.B. Robinson (Lauraceae) and its
ability to promote hair growth were investigated. Mucilage was obtained by boiling dried leaves and was spray dried to result in
the powder form. The cleaning property was investigated by examining the surface tension of the mucilage using a du Noüy ring
tensiometer. Mucilage powder appeared to reduce water surface tension to a minimum value of 44. 95 mN/ m when the
concentration of mucilage was increased to 20% (v/v) (equivalent to 460 μg/ml). A similar result was observed from mucilage in
its original liquid form. The hair growth modulating effect of mucilage was determined on human hair follicle dermal papilla
(HFDP) cell lines using the MTT assay. Prominent cell proliferation was observed at a concentration of 250 µg/ml of mucilage
after 24 h in culture (a 1.4-fold increase compared to the control).