Nanocrystalline copper(II) oxide-catalyzed one-pot four- component synthesis of polyhydroquinoline derivativesunder solvent-free conditions
Abstract
The efficient and environmentally friendly method for the one-pot synthesis of polyhydroquinolines has been developed in the presence of CuO nanoparticles. The multi-component reactions of aldehydes, dimedone, ethyl acetoacetate andammonium acetate were carried out under solvent-free conditions to afford some polyhydroquinoline derivatives. This method provides several advantages including high yields, low reaction times and little catalyst loading.
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74105
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safaeighomi2011nanocrystallinejournal
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