Naranjo Question Answering using End-to-End Multi-task Learning Model.

Naranjo Question Answering using End-to-End Multi-task Learning Model.

Rawat, Bhanu Pratap Singh;Li, Fei;Yu, Hong;
kdd : proceedings international conference on knowledge discovery & data mining 2019 Vol. 2019 pp. 2547-2555
227
rawat2019naranjokdd

Abstract

In the clinical domain, it is important to understand whether an adverse drug reaction (ADR) is caused by a particular medication. Clinical judgement studies help judge the causal relation between a medication and its ADRs. In this study, we present the first attempt to automatically infer the causality between a drug and an ADR from electronic health records (EHRs) by answering the Naranjo questionnaire, the validated clinical question answering set used by domain experts for ADR causality assessment. Using physicians' annotation as the gold standard, our proposed joint model, which uses multi-task learning to predict the answers of a subset of the Naranjo questionnaire, significantly outperforms the baseline pipeline model with a good margin, achieving a macro-weighted f-score between 0.3652 - 0.5271 and micro-weighted f-score between 0.9523 - 0.9918.

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