A bifunctional pyrazolone-chromone synthon directed organocatalytic double Michael cascade reaction: Forging five stereocenters in structurally diverse hexahydroxanthones

A bifunctional pyrazolone-chromone synthon directed organocatalytic double Michael cascade reaction: Forging five stereocenters in structurally diverse hexahydroxanthones

Liu, X.
Organic Chemistry Frontiers 2019 Vol. 6 pp. 1485-1490
205
liu2019aorganic

Abstract

An efficient method is reported to synthesize sulfonamides on DNA from sulfinic acids or sodium sulfinates and amines in the presence of iodine under mild conditions. This method demonstrates a major expansion of scope of sulfonamide formation on DNA through the utilization of a novel sodium carbonate-sodium sulfinate bifunctional reagent class.

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ID: 64686
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64686
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