Open Systems Pharmacology community - an open access, open source, open science approach to modeling and simulation in pharmaceutical sciences.
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Open Systems Pharmacology community - an open access, open source, open science approach to modeling and simulation in pharmaceutical sciences.

Lippert, Jörg;Burghaus, Rolf;Edginton, Andrea;Frechen, Sebastian;Karlsson, Mats;Kovar, Andreas;Lehr, Thorsten;Milligan, Peter;Nock, Valerie;Ramusovic, Sergej;Riggs, Matthew;Schaller, Stephan;Schlender, Jan;Schmidt, Stephan;Sevestre, Michaël;Sjögren, Erik;Solodenko, Juri;Staab, Alexander;Teutonico, Donato;
cpt: pharmacometrics & systems pharmacology 2019
345
lippert2019opencpt

Abstract

Systems Pharmacology integrates structural biological and pharmacological knowledge and experimental data enabling dissection of organism and drug properties and providing excellent predictivity. The development of systems pharmacology models is a significant task requiring massive amounts of background information beyond individual trial data. Qualification of models needs repetitive demonstration of successful predictions. Open Systems Pharmacology is a community that develops, qualifies and shares professional open source software tools and models in a collaborative open science way.

Keywords

Simulation PD open source modeling open science pharmacology systems pharmacology open access pbpk open innovation pk pharmaceutical sciences

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DOI:
10.1002/psp4.12473

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ID: 64434
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