Smart homes represent one of the principal points in the new ecosystem of the Internet of Things (IoT), both for the centrality of the home in the life of individuals and the significant potential concerning the diffusion of smart objects and innovative services. While IoT-oriented smart homes can revise how inhabitants interact with the domestic environment, each well-defined piece of technology necessitates precise network performance and distinct levels of security based on the sensitivity of the controlled system and the information it handles. This editorial presents a review of the papers accepted in the special issue. The issue has focused at obtaining high-quality papers aimed at solving well-known technical problems and challenges typical of IoT-oriented smart homes.