Diffuse multibacillary leprosy patient with Lucio’s phenomenon and positive anticardiolipin antibody misdiagnosed as lupus erythematosus panniculitis in the People’s Republic of China

Diffuse multibacillary leprosy patient with Lucio’s phenomenon and positive anticardiolipin antibody misdiagnosed as lupus erythematosus panniculitis in the People’s Republic of China

Wei Gao;Zhiming Chen;Haiqin Jiang;Ying Shi;Wenyue Zhang;Hongsheng Wang and
Infection and drug resistance 2019 Vol. 12 pp. 741-744
251
wei2019diffuseinfection

Abstract

Diffuse multibacillary leprosy patient with Lucio's phenomenon and positive anticardiolipin antibody misdiagnosed as lupus erythematosus panniculitis in the People's Republic of China Wei Gao, Zhiming Chen, Haiqin Jiang, Ying Shi, Wenyue Zhang, Hongsheng WangInstitute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Nanjing 210042, People’s Republic of ChinaAbstract: Lucio’s phenomenon (LP) is a special reactional state associated with diffuse multibacillary leprosy; both exhibit a limitative global distribution mainly in Mexico and Central America. We report a case of a 28-year-old female leprosy patient in the People’s Republic of China, together with LP and positive anticardiolipin antibody, characterized by vascular thrombosis and invasion of blood vessel walls by leprosy bacilli, causing extensive skin ulcers and followed by a large number of atrophic scars.Keywords: Leprosy, Lucio’s phenomenon, anticardiolipin antibody

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