Synthesis of some bis-triazole derivatives as probes for cytotoxicity study
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Synthesis of some bis-triazole derivatives as probes for cytotoxicity study

Al-Amin, Mohammad;Islam, M. Rabiul;
bangladesh journal of pharmacology 2006 Vol. 1 pp. -
295
alamin2006synthesisbangladesh

Abstract

A series of bis–[4-N-amino-5-mercapto-1,2,4-triazol-3-yl] alkanes (1a-e) and their Schiff bases with 2-adamanta-none (2a-d) and bis – [1, 2, 4-triazolo [3, 4-b] - 1, 3, 4-thiadiazol-4-yl] alkanes (3a-e) have been synthesized with high yields. The cytotoxicity study of these newly synthesized compounds against brine shrimp lethality test as well as Structure-Activity-Relationship (SAR) has been discussed.

Keywords

chemistry Organic Chemistry Therapeutics. Pharmacology Medicine Science arctic medicine. tropical medicine crystallography

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