Revisiting Centrioles in Nematodes—Historic Findings and Current Topics

Revisiting Centrioles in Nematodes—Historic Findings and Current Topics

Schwarz, Anna;Sankaralingam, Prabhu;O’Connell, Kevin F.;Müller-Reichert, Thomas;
Cells 2018 Vol. 7 pp. 101-
252
schwarz2018revisitingcells

Abstract

Theodor Boveri is considered as the “father” of centrosome biology. Boveri’s fundamental findings have laid the groundwork for decades of research on centrosomes. Here, we briefly review his early work on centrosomes and his first description of the centriole. Mainly focusing on centriole structure, duplication, and centriole assembly factors in C. elegans, we will highlight the role of this model in studying germ line centrosomes in nematodes. Last but not least, we will point to future directions of the C. elegans centrosome field.

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