Is whole-culture synchronization biology's 'perpetual-motion machine'?
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Is whole-culture synchronization biology's 'perpetual-motion machine'?

Cooper, Stephen;
Trends in Biotechnology 2004 Vol. 22 pp. 266-9
271
cooper2004istrends

Abstract

Whole-culture or batch synchronization cannot, in theory, produce a synchronized culture because it violates a fundamental law that proposes that no batch treatment can alter the cell-age order of a culture. In analogy with the history of perpetual-motion machines, it is suggested that the study of these whole-culture 'synchronization' methods might lead to an understanding of general biological principles even though these methods cannot be used to study the normal cell cycle.

Keywords

tolerance suppression effector regulation negative selection self-nonself discrimination

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DOI:
10.1016/j.tibtech.2004.04.009

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