Phenanthroline- BuOK Promoted Intramolecular C-H Arylation of Indoles with ArI under Transition-Metal-Free Conditions.

Phenanthroline- BuOK Promoted Intramolecular C-H Arylation of Indoles with ArI under Transition-Metal-Free Conditions.

Shan, Xiang-Huan;Yang, Bo;Zheng, Hong-Xing;Qu, Jian-Ping;Kang, Yan-Biao;
Organic letters 2018
283
shan2018phenanthroline-

Abstract

The first example of phenanthroline- BuOK promoted intramolecular radical C-H arylation of N-(2-iodobenzyl)indoles without involvement of transition metals has been developed. A variety of substituted 6 H-isoindolo [2, 1-a] indoles were prepared by a simple and efficient intramolecular cyclization using 1,10-phenanthroline in the presence of potassium tert-butoxide and chlorobenzene. This strategy provides a fast and versatile access to isoindolo[2,1- a]indole derivatives for the synthesis of pharmaceuticals and organic electroluminescent (EL) materials.

Citation

ID: 523
Ref Key: shan2018phenanthroline-
Use this key to autocite in SciMatic or Thesis Manager

References

Blockchain Verification

Account:
NFT Contract Address:
0x95644003c57E6F55A65596E3D9Eac6813e3566dA
Article ID:
523
Unique Identifier:
10.1021/acs.orglett.8b03449
Network:
Scimatic Chain (ID: 481)
Loading...
Blockchain Readiness Checklist
Authors
Abstract
Journal Name
Year
Title
5/5
Creates 1,000,000 NFT tokens for this article
Token Features:
  • ERC-1155 Standard NFT
  • 1 Million Supply per Article
  • Transferable via MetaMask
  • Permanent Blockchain Record
Blockchain QR Code
Scan with Saymatik Web3.0 Wallet

Saymatik Web3.0 Wallet