The permeable boundary between family life and professional life allows interferences between them which could lead to either positive or negative consequences in both plans of the employees’ lives. Our paper aims to analyse the relationships between the work-family conflict, organizational attachment, positive and negative affectivity, work satisfaction and life satisfaction and last but not least, well-being. The sample consisted of 245 employees. The main hypothesis highlights the mediating role of the work-family conflict in the relationship between affectivity, workplace attachment and job satisfaction and satisfaction with life. Future research could focus on the environmental factors mediating the relationships between life and job satisfaction and on their interaction with the dispositional factors.