Digitization is comparatively underdeveloped in the German healthcare system. Many digital applications are potentially capable of improving patient safety. This potential cannot be exploited in the long term with regional and time-limited projects. The present article shows in which care areas digital solutions are possible and necessary for safe patient care. In order for digital solutions and applications to be available to policyholders in the first healthcare market, producer of eHealth solutions will have to consider the goals of patient safety from the very beginning. In addition, processes and structures for proof of benefit must be implemented.