The 5'-3' distance of RNA secondary structures.
Abstract
Recently, Yoffe and colleagues observed that the average distances between 5'-3' ends of RNA molecules are very small and largely independent of sequence length. This observation is based on numerical computations as well as theoretical arguments maximizing certain entropy functionals. In this article, we compute the exact distribution of 5'-3' distances of RNA secondary structures for any finite n. Furthermore, we compute the limit distribution and show that for n = 30 the exact distribution and the limit distribution are very close. Our results show that the distances of random RNA secondary structures are distinctively lower than those of minimum free energy structures of random RNA sequences.
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47844
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0x95644003c57E6F55A65596E3D9Eac6813e3566dA
Article ID:
47844
Unique Identifier:
10.1089/cmb.2011.0301
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Scimatic Chain (ID: 481)
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