A recent flourishing of research is carried out jointly by psychologists and neuroscientists on management field. The new-born research field of Management Neuroscience involves a new kind of scientist and the ultimate goal of this research domain is to open the “black-box” to understand the behavioral and neural processes through which humans set communication and translate these behaviors into optimal choices. This paper aims to bring forward new results and fresh insights into this matter, taking into account both communication and the emotional components of this process. Starting by a distinction between conscious and unconscious mental processes, we see non-verbal components and their fundamental role in communicative process modulation. Finally verbal communication is treated with suggestions relevant for managers in regulating communication inside the company.