The objective of this study was to analyse the characteristics of the metal interface between the casting of a dental noble alloy and prefabricated gold copings (OCTA-ITI Implant System) after the fabrication procedures of a prosthetic implant-retained superstructure. The microscopical investigation, performed by optical microscopy (OM) and scanning electron microscopy (SEM), of the region around the cylinder after the casting process and the subsequent porcelain firing procedures showed the presence of an ideal interface, including: i) maintenance of coping and casting alloy microstructures up to the interface, and ii) absence of interfacial reaction products. A low content of porosity (less than 3% by volume in average) was observed in the casting alloy bulk as well as at interface. The investigation by energy-dispersive spectroscopy (EDS) of the alloy composition close to the interface showed the presence of a minimal elemental interdiffusion, suggesting that an adequate compatibility between alloy and coping characterized the materials used. A small decrease of the prefabricated coping hardness was also observed after the casting and porcelain firing procedures.