Open Versus Robotic Cystectomy: A Propensity Score Matched Analysis Comparing Survival Outcomes.

Open Versus Robotic Cystectomy: A Propensity Score Matched Analysis Comparing Survival Outcomes.

Moschini, Marco;Zamboni, Stefania;Soria, Francesco;Mathieu, Romain;Xylinas, Evanguelos;Tan, Wei Shen;Kelly, John D;Simone, Giuseppe;Meraney, Anoop;Krishna, Suprita;Konety, Badrinath;Mattei, Agostino;Baumeister, Philipp;Mordasini, Livio;Montorsi, Francesco;Briganti, Alberto;Gallina, Andrea;Stabile, Armando;Sanchez-Salas, Rafael;Cathelineau, Xavier;Rink, Michael;Necchi, Andrea;Karakiewicz, Pierre I;Rouprêt, Morgan;Koupparis, Anthony;Kassouf, Wassim;Scherr, Douglas S;Ploussard, Guillaume;Boorjian, Stephen A;Lotan, Yair;Sooriakumaran, Prasanna;Shariat, Shahrokh F;
journal of clinical medicine 2019 Vol. 8
281
moschini2019openjournal

Abstract

To assess the differential effect of robotic assisted radical cystectomy (RARC) versus open radical cystectomy (ORC) on survival outcomes in matched analyses performed on a large multicentric cohort.The study included 9757 patients with urothelial bladder cancer (BCa) treated in a consecutive manner at each of 25 institutions. All patients underwent radical cystectomy with bilateral pelvic lymphadenectomy. To adjust for potential selection bias, propensity score matching 2:1 was performed with two ORC patients matched to one RARC patient. The propensity-matched cohort included 1374 patients. Multivariable competing risk analyses accounting for death of other causes, tested association of surgical technique with recurrence and cancer specific mortality (CSM), before and after propensity score matching.Overall, 767 (7.8%) patients underwent RARC and 8990 (92.2%) ORC. The median follow-up before and after propensity matching was 81 and 102 months, respectively. In the overall population, the 3-year recurrence rates and CSM were 37% vs. 26% and 34% vs. 24% for ORC vs. RARC (all values > 0.1), respectively. On multivariable Cox regression analyses, RARC and ORC had similar recurrence and CSM rates before and after matching (all values > 0.1).Patients treated with RARC and ORC have similar survival outcomes. This data is helpful in consulting patients until long term survival outcomes of level one evidence is available.

Access

Citation

ID: 45316
Ref Key: moschini2019openjournal
Use this key to autocite in SciMatic or Thesis Manager

References

Blockchain Verification

Account:
NFT Contract Address:
0x95644003c57E6F55A65596E3D9Eac6813e3566dA
Article ID:
45316
Unique Identifier:
E1192
Network:
Scimatic Chain (ID: 481)
Loading...
Blockchain Readiness Checklist
Authors
Abstract
Journal Name
Year
Title
5/5
Creates 1,000,000 NFT tokens for this article
Token Features:
  • ERC-1155 Standard NFT
  • 1 Million Supply per Article
  • Transferable via MetaMask
  • Permanent Blockchain Record
Blockchain QR Code
Scan with Saymatik Web3.0 Wallet

Saymatik Web3.0 Wallet