We examined whether three types of personality (i.e. resilient, undercontrolled and overcontrolled) based on the Big Five personality taxonomy could be replicated among people living with HIV (PLWH). We also aimed to establish significant sociodemographic and clinical covariates of profile membership and verify whether these profiles are related to the subjective well-being (SWB) of participants.770 PLWH participated in this study. The Big Five personality traits were evaluated with the NEO-FFI questionnaire. SWB was operationalised by satisfaction with life (Satisfaction with Life Scale) and positive and negative affects (PANAS-X). Moreover, sociodemographic and clinical variables were collected.Latent profile analysis was used to identify personality types among participants. Instead of the three profiles most frequently reported in the literature, we identified a four-profile model (the resilient, undercontrolled, overcontrolled and the average profile type) as the best fit to the data. These profiles did not differ with regard to sociodemographic and clinical covariates. However, significant differences in SWB across profiles were noted, i.e. the highest SWB was observed among members of the resilient profile, and overcontrollers and undercontrollers were almost equally regarded as second best in SWB level, whereas the average profile consists of PLWH with the worst SWB.Identifying personality types in clinical settings enables more comprehensive understanding of interrelations between personality and health. Regarding PLWH, the typological approach may shed new light on ambiguous results devoted to the role of personality in well-being of these patients.