The aim of this study is to examine the impact of air pollutants, including mono-nitrogen oxides (NOx), nitrous oxide (NO), sulfur dioxide (SO), carbon dioxide emissions (CO), and greenhouse gas (GHG) emissions on ecological footprint, habitat area, food supply, and biodiversity in a panel of thirty-four developed and developing countries, over the period of 1995-2014. The results reveal that NOx and SO emissions both have a negative relationship with ecological footprints, while NO emission and real GDP per capita have a direct relationship with ecological footprints. NOx has a positive relationship with forest area, per capita food supply and biological diversity while CO emission and GHG emission have a negative impact on food production. NO has a positive impact on forest area and biodiversity, while SO emissions have a negative relationship with them. SO emission has a direct relationship with per capita food production, while GDP per capita significantly affected per capita food production and food supply variability across countries. The overall results reveal that SO, CO, and GHG emissions affected potential habitat area, while SO and GHG emissions affected the biodiversity index. Trade liberalization policies considerably affected the potential habitat area and biological diversity in a panel of countries.