The wastewater produced from the oilfield is chemically corrosive due to high salinity in combination with high temperatures. It is also rich in contaminants, such as oil, polyacrylamide, emulsions, suspended solid, etc. The density difference between the oil and water in the wastewater is low, which makes separation via gravity difficult. In this study, a combined pilot treatment is studied, which includes Fenton oxidation, settlement, activated carbon adsorption, and ultrafiltration (UF). The operational conditions of Fenton oxidation are optimized based on alleviating the fouling of the UF membrane. When the Fenton oxidation was operated at the molar ratio of HO to FeSO 3:1 and pH 2.2-2.5, the UF membrane could operate continuously for 20 h without cleaning. The membrane was fouled by the organics (oil/grease) and polymer, which can be effectively removed by composite cleaning reagent consisting of 0.1% NaOH and 0.1% sodium dodecylbenzenesulfonate (SDBS). With the UF treatment, the chemical oxygen demand (COD) of the effluent was less than 50 mg/L, which could meet the upgraded standard.