We report on a comprehensive method for analyzing landslide stability and the mitigation effect of countermeasures in this paper. The proposed method is a combination of theoretical method and numerical method. To address the uncertainties of the soil strength parameters, the rational values of these parameters are comprehensively determined by the back-analysis result of the reliability method and the result by the quantitative method, as well as the in-situ geological test. To evaluate the slope stability, the limit analysis using the 2D upper bound method and the FEM simulation using strength reduction method are performed, respectively. In order to illustrate the presented method, the so-called Lanmuxi landslide in China is selected as a case study. Results demonstrated that the stress and strain majorly concentrated at the toe and crown of the slope. According to the analysis results, countermeasures consisting of anchor lattice beams, landslide piles, and cracks filling, are suggested to reduce the failure risk of the landslide. Effect assessment based on the FEM analysis verifies the feasibility and effectiveness of the recommended countermeasures.