The comparative study was carried out concerning methods of flow cytofluorometry and optical microscopy in analysis of urine elements with the purpose of establishing the necessity of verification by physician the results of clinical diagnostic laboratory obtained by the analyzer. The final data concerning comparison of results obtained by two methodologies for various groups of pathology. The participation of physician in validation of results can be avoided in the groups with normal and exceeding standard values of content of corpuscular elements of urine. In the subgroups with pathological elements of urine (transitional and renal epithelium, pathological cylinders, crystals) it is recommended to implement analysis using cytofluorometric technique with subsequent verification by optical microscopy.