Nanotechnology is currently being widely employed in agriculture and horticulture. The most widely investigated and developed factor related to fruit trees is nanofertilizers (NFs), which play very important roles in increasing vegetative growth, improving reproductive growth and flowering, thereby increasing productivity, product quality and ultimately increasing shelf-life and decreasing fruit waste. These nanomaterials, which are generally sprayed at low concentrations on trees at different time intervals and in frequent sessions, are also considered as growth stimulants. Macro- and micro-scale NFs such as zinc, boron, chitosan, and fertilizer nanocomposites such as ZnFeMnB, NPKMg, and calcite have been shown to significantly improve the vegetative and reproductive traits of fruit trees such as pomegranate, strawberry, mango, date, coffee and grape. Knowledge on the effects of NFs on fruit trees and biological reasons for their effects on different traits is incomplete and there is an urgent need for extensive research on these topics. This article is protected by copyright. All rights reserved.