Breaking the cycle: treatment strategies for 163 cases of recurrent Clostridium difficile disease
Abstract
These data show that tapered or pulsed dosing regimens of vancomycin may result in a significantly better cure of RCDD. The persistence of C. difficile spores suggests that additional strategies to restore the normal colonic microflora may also be beneficial.
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
adult
female
male
adolescent
aged
middle aged
Recurrence
Remission Induction
risk factors
80 and over
Clinical Trial
Randomized Controlled Trial
Cohort Studies
anti-bacterial agents / therapeutic use*
metronidazole / therapeutic use*
enterocolitis
vancomycin / therapeutic use*
pseudomembranous / microbiology
lynne v mcfarland
clostridioides difficile*
pseudomembranous / drug therapy*
pmid:12135033
doi:10.1111/j.1572-0241.2002.05839.x
gary w elmer
christina m surawicz
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284016
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