Genetic rescue of Muenke syndrome model hearing loss reveals prolonged FGF-dependent plasticity in cochlear supporting cell fates
Abstract
Muenke syndrome model mice (Fgfr3P244R/+) have hearing loss associated with a supporting cell fate transformation of two Deiters' cells to two pillar cells. Mansour et al. find that the hearing loss is not rescued by reducing the FGFR3c ligand FGF8, ...
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