Pharmacological Studies of p, N-(3, 4-Methylenedioxy phenyl) Benzoic Acid (RRL-1364) - Part-I
Abstract
Detailed pharmacological investigations of p-N-(3, 4-methylene dioxy phenyl) benzoic acid revealed marked hypotensive action which was dose dependent and most marked in cats; it was absent in rats. Atropine could block this hypotensive action, thus suggest-ing cholinomimetic mechanism. Further studies indicated that the hypotension produced was central and possibly medullary in origin.
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276640
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