Evalution of the castrated male Sprague-Dawley rat as a model of the metabolic syndrome and type 2 diabetes
Abstract
Compared to humans rats respond differently to testosterone deficiency. Only few of the features typical for the human metabolic syndrome were observed in castrated male Sprague-Dawley rats. Therefore, we conclude that with the present experimental setup the castrated rat is not an optimal model for …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
pubmed abstract
nih
national institutes of health
national library of medicine
male
Disease Models
animal*
Rats
Sprague-Dawley
Random Allocation
body composition / physiology
Blood Glucose / metabolism
adipose tissue / metabolism
diabetes mellitus
area under curve
testosterone / blood*
type 2 / blood
testosterone / deficiency
type 2 / epidemiology
type 2 / etiology*
pmid:16505834
doi:10.1038/sj.ijo.0803261
b christoffersen
k raun
v golozoubova
metabolic syndrome / blood
metabolic syndrome / epidemiology
metabolic syndrome / etiology*
orchiectomy*
Access
Citation
ID:
274755
References
Blockchain Verification
Account:
NFT Contract Address:
0x95644003c57E6F55A65596E3D9Eac6813e3566dA
Article ID:
274755
Unique Identifier:
Network:
Scimatic Chain (ID: 481)
Loading...
Blockchain Readiness Checklist
Authors
Abstract
Journal Name
Year
Title
Creates 1,000,000 NFT tokens for this article
Token Features:
- ERC-1155 Standard NFT
- 1 Million Supply per Article
- Transferable via MetaMask
- Permanent Blockchain Record
Scan with Saymatik Web3.0 Wallet