Iron metabolism of established human hematopoietic cell lines in vitro
Abstract
Three malignant hematopoietic cell lines were used in studies on cellular iron metabolism. Our results show that iron-carrying transferrin became bound to specific dimeric cell surface receptors. Iron accumulated within the cell with time, whereas intact transferrin was released back to the medium. …
Keywords
leukemia
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
cell line
kinetics
lymphoma
iron / metabolism*
acute
macrophages / metabolism*
lymphocytes / metabolism*
erythrocytes / metabolism*
transferrin / metabolism*
ammonium chloride / pharmacology
chloroquine / pharmacology
pmid:6573263
doi:10.1016/0014-4827(83)90411-1
k forsbeck
k nilsson
endocytosis / drug effects
ferritins / metabolism
heme / biosynthesis
erythroblastic
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274647
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