Interaction of D-type cyclins with a novel myb-like transcription factor, DMP1
Abstract
The cyclin D-dependent kinases CDK4 and CDK6 trigger phosphorylation of the retinoblastoma protein (RB) late in G1 phase, helping to cancel its growth-suppressive function and thereby facilitating S-phase entry. Although specific inhibition of cyclin D-dependent kinase activity in vivo can prevent c …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
Molecular
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
u.s. gov't
amino acid sequence
Comparative Study
P.H.S.
cell line
3T3 Cells
Transcription Factors / metabolism*
Base Sequence
sequence homology
amino acid
kinetics
cloning
recombinant proteins / biosynthesis
transcription factors / biosynthesis
transfection
phosphorylation
dna / metabolism
binding sites
consensus sequence
recombinant proteins / metabolism
transcription factors / chemistry
spodoptera
protein-serine-threonine kinases / metabolism
c j sherr
cyclin-dependent kinase 4
proto-oncogene proteins / chemistry
cyclin d
retinoblastoma protein / metabolism
saccharomyces cerevisiae
pmid:8887674
pmc231647
doi:10.1128/mcb.16.11.6457
h hirai
cyclin-dependent kinase 6
cyclin-dependent kinases / metabolism
cyclins / metabolism*
proto-oncogene proteins c-myb
recombinant proteins / chemistry
trans-activators / chemistry
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274643
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