Chromosome condensation by a human condensin complex in Xenopus egg extracts
Abstract
13S condensin is a five-subunit protein complex that plays a central role in mitotic chromosome condensation. The condensin complex was originally identified and purified from Xenopus egg extracts and shown to have an ATP-dependent positive supercoiling activity in vitro. We report here the characte …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Molecular
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
u.s. gov't
female
amino acid sequence
P.H.S.
DNA
Sequence Analysis
DNA-Binding Proteins / metabolism*
Nuclear Proteins / metabolism*
Molecular Sequence Data
complementary / genetics
sequence homology
amino acid
cloning
hela cells
phosphorylation
nucleic acid conformation
adenosine triphosphatases / metabolism*
cell-free system
xenopus
k kimura
t hirano
chromosomes / metabolism*
multiprotein complexes
cyclin b / metabolism
cdc2 protein kinase / metabolism
superhelical / metabolism*
protein subunits
pmid:11136719
doi:10.1074/jbc.c000873200
o cuvier
chromosomes / ultrastructure*
ovum / metabolism
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274571
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