The yeast polo kinase, Cdc5, regulates the shape of the mitotic nucleus

The yeast polo kinase, Cdc5, regulates the shape of the mitotic nucleus

Alison D. Walters, Christopher K. May, Emma S. Dauster, Bertrand P. Cinquin, Elizabeth A. Smith, Xavier Robellet, Damien D’Amours, Carolyn A. Larabell, Orna Cohen-Fix;Alison D. Walters;Christopher K. May;Emma S. Dauster;Bertrand P. Cinquin;Elizabeth A. Smith;Xavier Robellet;Damien D’Amours;Carolyn A. Larabell;Orna Cohen-Fix;
Current biology : CB 2014 Vol. 24 pp. 2861-
91
cohen-fix2014currentthe

Abstract

Abnormal nuclear size and shape are hallmarks of aging and cancer [, ]. However, the mechanisms regulating nuclear morphology and nuclear envelope (NE) expansion are poorly understood. In metazoans, the NE disassembles prior to chromosome segregation ...

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