Reconstitution of mitotic chromatids with a minimum set of purified factors

Reconstitution of mitotic chromatids with a minimum set of purified factors

Shintomi K;Takahashi TS;Hirano T;;
Nature Cell Biology 2015 Vol. 17 pp. -
219
k2015naturereconstitution

Abstract

The assembly of mitotic chromosomes, each composed of a pair of rod-shaped chromatids, is an essential prerequisite for accurate transmission of the genome during cell division. It remains poorly understood, however, how this fundamental process might be achieved and regulated in the cell. Here we r …

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