Regulation of Wnt/beta-catenin signaling by protein kinases
Abstract
The Wnt/beta-catenin signaling pathway plays essential roles during development and adult tissue homeostasis. Inappropriate activation of the pathway can result in a variety of malignancies. Protein kinases have emerged as key regulators at multiple steps of the Wnt pathway. In this review, we prese …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
review
pubmed abstract
nih
national institutes of health
national library of medicine
models
research support
non-u.s. gov't
N.I.H.
Extramural
biological
embryonic development / physiology*
phosphorylation
signal transduction / physiology*
beta catenin / metabolism*
repressor proteins / metabolism
wnt proteins / metabolism*
homeostasis / physiology*
gene expression regulation / physiology*
protein kinases / metabolism*
pmid:19623618
pmc3173947
doi:10.1002/dvdy.22019
esther m verheyen
cara j gottardi
axin protein
Citation
ID:
274453
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