The budding yeast silencing protein Sir1 is a functional component of centromeric chromatin

The budding yeast silencing protein Sir1 is a functional component of centromeric chromatin

Sharp JA;Krawitz DC;Gardner KA;Fox CA;Kaufman PD;;
genes & development 2003 Vol. 17 pp. -
292
ja2003genesthe

Abstract

In fission yeast and multicellular organisms, centromere-proximal regions of chromosomes are heterochromatic, containing proteins that silence gene expression. In contrast, the relationship between heterochromatin proteins and kinetochore function in the budding yeast Saccharomyces cerevisiae remain …

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