The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
Abstract
HMGA2, a high-mobility group protein, is oncogenic in a variety of tumors, including benign mesenchymal tumors and lung cancers. Knockdown of Dicer in HeLa cells revealed that the HMGA2 gene is transcriptionally active, but its mRNA is destabilized in ...
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274201
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274201
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10.1101/gad.1540407
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