Amikacin use and therapeutic drug monitoring in adults: do dose regimens and drug exposures affect either outcome or adverse events? A systematic review
Abstract
This systematic review found little published evidence to support an optimal dosage regimen or TDM targets for amikacin therapy. The use of alternative approaches, such as consensus opinion and a review of current practice, will be required to develop guidelines to maximize therapeutic outcomes and …
Keywords
systematic review
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
review
humans
pubmed abstract
nih
national institutes of health
national library of medicine
treatment outcome
adult
anti-bacterial agents / therapeutic use
anti-bacterial agents / administration & dosage*
dose-response relationship
drug
drug-related side effects and adverse reactions
amikacin / adverse effects*
anti-bacterial agents / adverse effects*
drug monitoring*
amikacin / therapeutic use
amikacin / administration & dosage*
anti-bacterial agents / blood
amikacin / blood
investigators=[]
affs=[])
pmid:27494904
doi:10.1093/jac/dkw250
abi jenkins
alison h thomson
collabauthor(name='(bsac working party on therapeutic drug monitoring)'
interrupted time series analysis
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274199
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